lin Gastroenterol Hepatol. 2007 Apr
Prevalence of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.
Gambarin-Gelwan M, Kinkhabwala SV, Schiano TD, Bodian C, Yeh HC, Futterweit W.
Division of Gastroenterology and Hepatology, Weill Medical College of Cornell University, New York, NY 10021, USA.mag2046@med.cornell.edu
BACKGROUND & AIMS: Insulin resistance has been implicated in the pathogenesis of both nonalcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS). We hypothesized that NAFLD would be common in both obese and nonobese women with PCOS. The aim of this study was to estimate the prevalence of and identify associated factors for hepatic steatosis in women with PCOS.
CONCLUSIONS: Fatty liver was identified in 55% of subjects with PCOS, nearly 40% of whom were lean women. High BMI and insulin resistance appeared to be important associated factors. Early recognition of NAFLD in this group of young patients is warranted, and further investigation including liver biopsy might be indicated.
METHODS: This is a retrospective study of 88 consecutive premenopausal women with PCOS. Clinical history, height, weight, and laboratory values were obtained. Fasting measurements of serum glucose and insulin were used to calculate homeostasis model assessment of insulin resistance (HOMA-IR). Abdominal ultrasonography was used to determine the presence and severity of hepatic steatosis.
RESULTS: Of the 88 women (median age, 31.4 years), 48 (55%) had steatosis; 15 (39%) of them were lean women. The presence of steatosis was associated with a greater body mass index (BMI) (P = .005) and HOMA-IR (P = .033), a lower fasting high-density lipoprotein (P = .003), and a greater prevalence of impaired fasting glucose, impaired glucose tolerance, and diabetes mellitus (P = .013). Only 7 (15%) subjects with hepatic steatosis had abnormal liver chemistries.
Polycystic ovary syndrome (PCOS) is a condition that affects a woman's hormone levels. Women with PCOS produce higher-than-normal amounts of male hormones. This hormone imbalance causes them to skip menstrual periods and makes it harder for them to get pregnant.But with Agbara Herbal Cleanser, This Pcos will be cured and it will regulate and balance your Hormones and You will get Pregnant very easy, Use Agbara Herbal Cleanser , Cure your Pcos and get pregnant very fast. The cysts are not harmful, but they can lead to an imbalance in hormone levels. Women with PCOS may also experience menstrual cycle abnormalities, increased androgen (sex hormone) levels, excess hair growth, acne, and obesity…
ReplyDeleteMost ovarian cysts are small and don't cause symptoms. If a cyst does cause symptoms, you may have pressure, bloating, swelling, or pain in the lower abdomen on the side of the cyst. This pain may be sharp or dull and may come and go. If a cyst ruptures, it can cause sudden, severe pain., To avoid all this pains and cure it completely, Just use Agbara Herbal Deep Cleanser, and everything will be clear and you can get pregnant without any problem. drcureherbalhome@gmail.com.
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